The Aging, Dementia and Traumatic Brain Injury Study is a detailed neuropathologic, molecular and transcriptomic characterization of brains of control and TBI exposure cases from a unique aged population-based cohort from the Adult Changes in Thought (ACT) study.
The Aging, Dementia and Traumatic Brain Injury Study was developed by a consortium consisting of the University of Washington, Group Health Research Institute and the Allen Institute for Brain Science.
The study was supported by the Paul G. Allen Family Foundation (PIs: Richard Ellenbogen and C. Dirk Keene, University of Washington; PI: Eric Larson, Group Health Research Institute; and PI: Ed Lein, Allen Institute for Brain Science).
The ACT study is a longitudinal population-based prospective cohort study of brain aging and incident dementia in the Seattle metropolitan area. ACT is a repository at the Group Health Research Institute (GHRI), which has established policies and procedures for sharing data with external investigators. Data available from this study web site do not require any additional Institutional Review Board (IRB) approval or permissions. Linking those data with other ACT study or Group Health data would require additional review. All of those steps are initiated after contacting ACTproposals@ghc.org.